Publicaciones últimos 5 años

Kerkhof PLM, Diaz-Navarro RA, Handly N. Cardiology without ejection fraction. Br J Cardiol 2025;32:148–51doi:10.5837/bjc.2025.052

Kerkhof PLM, Diaz-Navarro RA, Li JK, Handly N. Analytical Expression for the Dependence of Ejection Fraction on End-systolic or End-diastolic Volume. Annu Int Conf IEEE Eng Med Biol Soc. 2025 Jul;2025:1-4. doi: 10.1109/EMBC58623.2025.11254494. PMID: 41336601.

Jiménez-Jara C, Salas R, Díaz-Navarro R, Chabert S, Andia ME, Vega J, Urbina J, Uribe S, Sekine T, Raimondi F, Sotelo J. AI Applied to Cardiac Magnetic Resonance for Precision Medicine in Coronary Artery Disease: A Systematic Review. J Cardiovasc Dev Dis. 2025 Sep 9;12(9):345. doi: 10.3390/jcdd12090345. PMID: 41002624; PMCID: PMC12470487

Kerkhof PLM, Diaz-Navarro RA, Handly N. A comprehensive analysis of ratio-based metrics in physiology. J Physiol. 2025 Feb;603(4):1007-1008. doi: 10.1113/JP287889. Epub 2024 Dec 9. PMID: 39651899.

Peter L M Kerkhof, Rienzi A. Diaz-Navarro, Neal Handly. How the crystal ball helps to beat ejection fraction as predictor of mortality after myocardial infarction. Echocardiography 2024 Oct;41 (10):e15936. doi: 10.1111/echo.15936.

Rienzi A Diaz-Navarro, Peter L M Kerkhof. Cardiac ejection fraction as a problematic metric for heart failure phenotyping. Br J Cardiol 2024;31:45–8. doi:10.5837/bjc.2024.019.

Díaz-Navarro R, Sáez T, Peirano F, Silva D. Miocardio salvado en infarto agudo de miocardio con supradesnivel del ST post reperfusión: Análisis mediante resonancia magnética cardiaca. Rev. méd. Chile 2023; 151:1164-1176.

Díaz-Navarro R, Sáez T. Síndrome de Takotsubo: Actualización 2022. Rev Med Chile 2023; 151: 1053-1070.

P L Kerkhof, G R Heyndrickx, R A Diaz-Navarro, N Handly, Heterogeneity of patients phenotyped as heart failure with mildly reduced ejection fraction. European Heart Journal, Volume 44, Issue Supplement_2. doi: 10.1093/eurheartj/ehad655.825.

Kerkhof PLM, Wuhl E, Diaz-Navarro RA, Handly N, Li JK. Pulse Pressure is Sex-Specifically Associated with the Ratio of Diastolic and Systolic Arterial Pressure in Healthy Children, and Differently During Night Versus Daytime Recordings. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul; 2023:1-4. doi:1109/EMBC40787.2023.10340234.

Kerkhof PLM, Diaz-Navarro RA, Heyndrickx GR, Li JK, Handly N. Sex-specific Evaluation of Ventricular Ejection Fraction and End-Systolic Volume Applied to Cardiac Resynchronization Therapy. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul; 2023:1-4. Doi: 1109/EMBC40787.2023.10340917.

Kerkhof PLM, Bell-Beringer JY, Diaz-Navarro RA, K-J Li J, Handly N. Ventricular Ejection Fraction and Global Strains in Connection with the Volume Regulation Graph. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul; 2023:1-4. Doi: 10.1109/EMBC40787.2023.10339941.

Peter LM Kerkhof, John K-J. Li, Rienzi A Diaz-Navarro, Guy R Heyndrickx, Theo JC Faes, Francesco Tona, Neal Handly. Analysis and Interpretation of Primary and Derived Data Sets in Cardiology. World Sci Annu Rev Biomech. 2023; 1: 1-23. DOI: 10.1142/S2810958923300032.

Kerkhof PLM, Diaz-Navarro RA. Prediction of a super-response to cardiac resynchronization therapy as guided by left ventricular end-systolic volume size. J Clin Ultrasound. 2023 Mar;51(3):394-397. doi: 10.1002/jcu.23393. PMID: 36893040.

Diaz-Navarro RA, Kerkhof PLM. Case report on right ventricular mural endocarditis, not diagnosed clinically, but histopathologically after cardiac surgery. Eur Heart J Case Rep. 2022 Sep 15;6(9): ytac376. doi: 10.1093/ehjcr/ytac376. PMID: 36187935; PMCID: PMC9518669. 

Peter L M Kerkhof, Guy R Heyndrickx, Rienzi A Diaz-Navarro, Elena-Laura Antohi, Serban Mihaileanu, Neal Handly. Ventricular and Atrial Ejection Fractions are Associated with Mean Compartmental Cavity Volume in Cardiac Disease. Annu Int Conf IEEE Eng Med Biol Soc 2022 Jul; 2022:1384-1387. doi: 10.1109/EMBC48229.2022.9871315.

Peter L M Kerkhof, Rienzi A Diaz-Navarro, Guy R Heyndrickx, Aleksandra O Konradi, Evgeny V Shlyakhto, Neal Handly, John K-J Li. The Ratio of Diastolic and Systolic Arterial Pressure is Associated with Pulse Pressure. Annu Int Conf IEEE Eng Med Biol Soc 2022 Jul; 2022:1-4. doi: 10.1109/EMBC48229.2022.9871478.

Kerkhof Peter LM., Díaz-Navarro Rienzi, Heyndrickx Guy R., Handly Neal. La serendipia en torno la fracción de eyección: una revisión de la historia, la casualidad y la cuasi-funcionalidad de una métrica aplaudida. Rev. méd. Chile 2022; 150(2): 232-240. dx.doi.org/10.4067/S0034-98872022000200232.

Díaz-Navarro R, Poloni-Izeta D, Silva-González D. Estrés emocional relacionado con un terremoto como factor causante de un síndrome de takotsubo [Takotsubo syndrome associated with an earthquake. report of two cases]. Rev Med Chil. 2021 Dec;149(12):1801-1805. doi: 10.4067/s0034-98872021001201801. PMID: 35735348.

Díaz-Navarro Rienzi, Pepe Valenzuela Rodrigo, Silva González Danilo. El rol de la resonancia magnética cardíaca en el diagnóstico diferencial entre miocarditis aguda e infarto agudo de miocardio con elevación del segmento ST. Rev. méd. Chile 2021; 149(10): 1399-1411. http://dx.doi.org/10.4067/s0034-98872021001001399.

Kerkhof PLM, Diaz-Navarro RA, Handly N. What reveals the right ventricle about prognosis in heart failure, and why appear metrics to be sex-specific? J Clin Ultrasound. 2021 Sep 18. doi: 10.1002/jcu.23070. Online ahead of print. PMID: 34536022 No abstract available.

Diaz-Navarro RA, Kerkhof PLM. Left Ventricular Global Function Index and the Impact of its Companion Metric. Front Cardiovasc Med. 2021 Aug 30; 8:695883. doi: 10.3389/fcvm.2021.695883. PMID: 34527709; PMCID: PMC8435684.      

Diaz-Navarro R, Urrutia G, Cleland JGF, Poloni D, Villagran F, Acosta-Dighero R, Bangdiwala SI, Rada G, Madrid E. Stem cell therapy for dilated cardiomyopathy. Cochrane Database of Systematic Reviews 2021, Issue 7. Art. No.: CD013433. DOI: 10.1002/14651858.CD013433.pub2.

Díaz-Navarro R. Takotsubo syndrome: the broken-heart syndrome. Br J Cardiol. 2021 Mar 9;28(1):11. doi: 10.5837/bjc.2021.011. PMID: 35747479; PMCID: PMC8822514.

Díaz-Navarro R, Silva González D, Henríquez-Roldán C. Valor de la resonancia magnética cardíaca para el diagnóstico diferencial en pacientes con sospecha de infarto agudo de miocardio con elevación del segmento ST y arterias coronarias normales [Cardiac magnetic resonance imaging in patients with a suspected myocardial infarction and normal coronary arteries]. Rev Med Chil. 2020 oct;148(10):1406-1417. Spanish. doi: 10.4067/S0034-98872020001001406. PMID: 33844710.

Diaz R, Silva D. The role of cardiac magnetic resonance imaging in differentiating acute myocarditis from acute ST-elevation myocardial infarction. Eur Heart J. Acute Cardiovasc Care, Volume 9, Issue 2_suppl, 1 August 2020, Pages 1–196 (p 117). doi.org/10.1177/2048872620937980.

Díaz-Navarro R. Transposición congénitamente corregida de grandes arterias en adultos asintomáticos diagnosticada circunstancialmente por ecocardiografía. Casos clínicos [Asymptomatic congenitally corrected transposition of the great arteries. Report of two cases]. Rev Med Chil. 2020 Jun;148(6):868-874. Spanish. doi: 10.4067/S0034-98872020000600868. PMID: 33480388.

Diaz-Navarro RA, Kerkhof Peter LM. Global Longitudinal Strain, Ejection Fraction, Ventriculo-Arterial Coupling and Their Interrelationships in Heart Failure Patients with Different Phenotypes. The FASEB Journal 34(S1):1-1. DOI: 10.1096/fasebj.2020.34. s1.04342.

Diaz‐Navarro R, Urrutia G, Cleland JGF, Poloni D, Villagran F, Bangdiwala S, Rada G, Madrid E. Stem cell therapy for dilated cardiomyopathy. Cochrane Database of Systematic Reviews 2019, Issue 9. Art. No.: CD013433. DOI: 10.1002/14651858.CD013433.

Díaz-Navarro R, Carmen Pérez. Terapia de células madre e insuficiencia cardiaca: aspectos éticos. Rev. Med. Chile Vol. 147: 787-789, Nº6, Junio 2019. https://dx.doi.org/10.4067/S0034-98872019000600787

Díaz-Navarro R, Parraga M. Usselfulness of cardiac magnetic resonance imaging in limble-girdle muscular dystrophy with cardiac involvement. European Heart Journal – Cardiovascular Imaging, Volume 20, Supplement_2, June 2019, pages ii290, abstract P380. https://doi10.1093/ehjci/jez109.021

Valencia S, Peirano F, Xi W, Han YS, Diaz R, Sieck G. Ischemia/Reperfusion‐Induced Reduction of Ca 2+ Sensitivity in Isolated Cardiomyocytes. The FASEB Journal 33(S1). doi.org/10.1096/fasebj.2019.33.1_supplement.690.1.

Díaz-Navarro R, Silva D. Usefulness of cardiac magnetic resonance for the differential diagnosis of acute heart conditions mimicking myocardial infarction. European Heart Journal – Cardiovascular Imaging, Volume 20, Issue Supplement_1,1 January 2019, pages i1132, abstract P1561.https://doi.org/10.1093/ehjci/jey273

Sofía Adasme-Reyes, Diana Silva-Castro, Constanza Rimassa-Taré, Tamara Sáez Gutiérrez, Jaime A. Riquelme. Fármacos antidiabéticos en cardioprotección: más allá del control de la glicemia. Revista Salud y Ciencia Vol.1, Nº 1, 2025.

Díaz-Navarro R, Sáez T, Peirano F, Silva D. Miocardio salvado en infarto agudo de miocardio con supradesnivel del ST post reperfusión: Análisis mediante resonancia magnética cardiaca. Rev. méd. Chile 2023; 151:1164-1176.

Díaz-Navarro R, Sáez T. Síndrome de Takotsubo: Actualización 2022. Rev Med Chile 2023; 151: 1053-1070.

Villalobos-Labra R, Liu R, Spaans F, Sáez T, Semeria Maitret T, Quon A, Sawamura T, Cooke CM, Davidge ST. Placenta-Derived Extracellular Vesicles From Preeclamptic Pregnancies Impair Vascular Endothelial Function via Lectin-Like Oxidized LDL Receptor-1. Hypertension. 2023 Oct;80(10):2226-2238. doi: 10.1161/HYPERTENSIONAHA.123.21205. Epub 2023 Aug 24. 

Sáez T, Pageé A, Kirschenman R, Quon A, Spaans F, Davidge ST. A High Cholesterol Diet During Late Pregnancy Impairs Long-Term Maternal Vascular Function in Mice. Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):120-132.

Villalobos-Labra R, Liu R, Spaans F, Sáez T, Quon A, Wong M, Pink D, Lewis J, Vatish M, Davidge ST, Cooke CM. Placenta-derived extracellular vesicles from preeclamptic and healthy pregnancies impair ex vivo vascular endothelial function. Biosci Rep. 2022 Dec 22;42(12):BSR20222185.

Wooldridge AL, Pasha M, Chitrakar P, Kirschenman R, Quon A, Spaans F, Sáez T, Cooke CM, Davidge ST. (2022) Advanced Maternal Age Impairs Uterine Artery Adaptations to Pregnancy in Rats. Int J Mol Sci. 23(16):9191.

Sáez T, Wiley C, Quon A, Spaans F, Davidge ST. (2021) Increased oxidative stress and endothelial activation in umbilical veins from pregnancies diagnosed with preeclampsia. Pregnancy Hypertens. 26:87-90.

Sáez T, Spaans F, Kirschenman R, Sawamura T, Davidge ST. (2020). Original Research: High-cholesterol diet during pregnancy induces maternal vascular dysfunction in mice: potential role for oxidized LDL- induced LOX-1 and AT1 receptor activation.ClinSci(Lond).134(17):2295-2313.

Sáez T, de Vos P, Kuipers J, Sobrevia L, Faas MM. (2019). OriginalResearch: Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high D-glucose conditions. Immunobiology. 224(2):325-333.

Sáez T, Toledo F, Sobrevia L. (2019). Review: Impaired signalling pathways mediated by extracellular vesicles in diabesity. Mol Aspects Med. 66:13-20.